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Tamoxifendid eventually receive marketing approval as a fertility treatment, but the class of compounds never proved useful in human contraception.
The binding of [3H]tamoxifen ([3H]Tam), a nonsteroidal antiestrogen, and of 4-[ 3H]hydroxytamoxifen ([3H]OH-Tam), a metabolite accumulated in vivo in target ...
Clin Exp Metastasis. 2004;21(3):201-12. Tamoxifen resistance in breast cancer cells is accompanied by an enhanced motile and invasive phenotype: inhibition ...
The metabolism of tamoxifen was examined in the rat, mouse, and human ... Large oral doses of tamoxifen (200 mg/kg) in the immature ovariectomized rat and ...
OBJECTIVE: To compare the effect of two ovulation-inducing agents, clomiphene citrate and tamoxifen, on cervical mucus and sperm-cervical mucus interaction.
Tamoxifen citrate has a molecular weight of 563.62, the pKa' is 8.85, the equilibrium solubility in water at 37°C is 0.5 mg/mL and in 0.02 N HCl at 37°C, it is 0.2 ...
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